| ACROSS
1. A workplace for the conduct of scientific research.
4. A short labored intake of breath with the mouth open.
8. A period marked by distinctive character or reckoned from a fixed point or event.
11. The sign language used in the United States.
12. Type genus of the Alcidae comprising solely the razorbill.
13. A metric unit of volume or capacity equal to 10 liters.
14. Not only so, but.
16. An anxiety disorder characterized by chronic free-floating anxiety and such symptoms as tension or sweating or trembling of light-headedness or irritability etc that has lasted for more than six months.
17. A nucleic acid consisting of large molecules shaped like a double helix.
18. The United Nations agency concerned with atomic energy.
19. The blood group whose red cells carry both the A and B antigens.
21. An associate degree in nursing.
22. Small cubes with 1 to 6 spots on the faces.
23. (Akkadian) God of wisdom.
25. The elementary stages of any subject (usually plural).
26. A federal agency established to regulate the release of new foods and health-related products.
30. West Indian tree having racemes of fragrant white flowers and yielding a durable timber and resinous juice.
35. Jordan's port.
37. Soreness and warmth caused by friction.
39. Large burrowing rodent of South and Central America.
42. A city in the European part of Russia.
43. Being one more than two.
45. (usually followed by `of') Released from something onerous (especially an obligation or duty).
46. A flat wing-shaped process or winglike part of an organism.
47. A Kwa language spoken in Ghana and the Ivory Coast.
48. An edge tool with a heavy bladed head mounted across a handle.
49. A soft silvery metallic element of the alkali earth group.
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DOWN
1. Genus of western United States annuals with showy yellow or white flowers.
2. An association of nations dedicated to economic and political cooperation in southeastern Asia.
3. (Scottish) Bluish-black or gray-blue.
4. A rare silvery (usually trivalent) metallic element.
5. Primitive chlorophyll-containing mainly aquatic eukaryotic organisms lacking true stems and roots and leaves.
6. Someone who works (or provides workers) during a strike.
7. A number of sheets of paper fastened together along one edge.
8. Tropical starchy tuberous root.
9. Type genus of the Ranidae.
10. By bad luck.
15. A pilgrimage to Mecca.
20. Any of numerous local fertility and nature deities worshipped by ancient Semitic peoples.
24. Light informal conversation for social occasions.
27. Any of various spiny trees or shrubs of the genus Acacia.
28. A hard gray lustrous metallic element that is highly corrosion-resistant.
29. A city in western Germany near the Dutch and Belgian borders.
31. A loose sleeveless outer garment made from aba cloth.
32. A white soft metallic element that tarnishes readily.
33. A linguistic element added to a word to produce an inflected or derived form v 1.
34. English economist noted for his studies of international trade and finance (born in 1907).
36. A hardy cabbage with coarse curly leaves that do not form a head.
38. A sensation (as of a cold breeze or bright light) that precedes the onset of certain disorders such as a migraine attack or epileptic seizure.
39. (Irish) Mother of the ancient Irish gods.
40. East Indian tree bearing a profusion of intense vermilion velvet-textured blooms and yielding a yellow dye.
41. Title for a civil or military leader (especially in Turkey).
44. A white metallic element that burns with a brilliant light.
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