| ACROSS
1. Cassava with long tuberous edible roots and soft brittle stems.
5. An antibody in blood serum that attaches to invading microorganisms and other antigens to make them more susceptible to the action of phagocytes.
12. Legal document setting forth rules governing a particular kind of activity.
15. Of or relating to near the ear.
16. Spotted crakes.
17. An agency of the United Nations affiliated with the World Bank.
18. Any fungus of the family Boletaceae.
20. The state or fact of existing.
21. (British) A waterproof raincoat made of rubberized fabric.
22. A medicinal drug used to evoke vomiting (especially in cases of drug overdose or poisoning).
23. A liquid used for printing or writing or drawing.
24. The mission in San Antonio where in 1836 Mexican forces under Santa Anna besieged and massacred American rebels who were fighting to make Texas independent of Mexico.
26. A state in northwestern North America.
29. Either of two folds of skin that can be moved to cover or open the eye.
33. Any of the large anthropoid apes of the family Pongidae.
38. Water frozen in the solid state.
39. A unit of length of thread or yarn.
41. A member of the North American Indian people of the Pit river valley in northern California.
43. A cruel and brutal fellow.
44. A city in southeastern Spain.
46. (usually followed by `of') Released from something onerous (especially an obligation or duty).
47. The basic monetary unit of most members of the European Union (introduced in 1999).
48. Cubes of meat marinated and cooked on a skewer usually with vegetables.
51. A brittle silver-white metalloid element that is related to selenium and sulfur.
53. A ductile gray metallic element of the lanthanide series.
58. The capital and largest city of Bangladesh.
61. A happening that is distinctive in a series of related events.
63. Type genus of the Rhamnaceae.
67. 10 grams.
68. Spread abroad or out.
71. Title for a civil or military leader (especially in Turkey).
72. A loose sleeveless outer garment made from aba cloth.
73. A desert in southwestern Africa - largely Botswana.
74. Not in good physical or mental health.
75. The month following February and preceding April.
76. A peninsula in southwestern Asia that forms the Asian part of Turkey.
77. Meeting adequate standards for a purpose.
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DOWN
1. A desert in central Asia.
2. On, to, or at the top.
3. Cause annoyance in.
4. A mass of ice and snow that permanently covers a large area of land (e.g., the polar regions or a mountain peak).
5. An organization of countries formed in 1961 to agree on a common policy for the sale of petroleum.
6. A radioactive metallic element that is similar to tellurium and bismuth.
7. A historical region in central and northern Yugoslavia.
8. A chronic disease of the nose characterized by a foul-smelling nasal discharge and atrophy of nasal structures.
9. A Dravidian language spoken in south central India.
10. A hotel providing overnight lodging for travelers.
11. Kamarupan languages spoken in northeastern India and western Burma.
12. Capital and largest city and economic center of Peru.
13. (Old Testament) In Judeo-Christian mythology.
14. A city in east central Texas.
19. A member of a North American Indian people of southwestern Oregon.
25. (of tempo) Slow adv.
27. A member of a widespread group of Amerindians living in northeastern South America.
28. Any of various primates with short tails or no tail at all.
30. Grow by addition, as of capital.
31. Hungarian composer of light operas (1870-1948).
32. A small ball with a hole through the middle.
34. A chalcedony with alternating black and white bands.
35. United States writer (born in Lebanon) (1883-1931).
36. Take in, also metaphorically.
37. Something whose name is either forgotten or not known.
40. A South American shrub whose leaves are chewed by natives of the Andes.
42. Genus of European subshrubs or herbs having pink or purple or yellow solitary or clustered flowers.
45. In bed.
49. An international organization of European countries formed after World War II to reduce trade barriers and increase cooperation among its members.
50. A fraudulent business scheme.
52. (statistics) Relating to or constituting the middle value of an ordered set of values (or the average of the middle two in an even-numbered set).
54. The French-speaking part of the Canadian Maritime Provinces.
55. A roll of tobacco for smoking.
56. Unaged colorless liquor originating in Russia.
57. A unit of magnetic flux density equal to one weber per square meter.
59. Of or relating to or involving an area.
60. An African river that flows northwest into Lake Chad.
62. A metabolic acid found in yeast and liver cells.
64. Marked by or showing unaffected simplicity and lack of guile or worldly experience.
65. Large sweet juicy hybrid between tangerine and grapefruit having a thick wrinkled skin.
66. Containing or filled with salt.
69. Having only superficial plausibility.
70. The 17th letter of the Greek alphabet.
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